Integra, and 0.991 for Integra vs. Afinion. The average biases of AZD3965 research buy HbA(1c) Afinion (IFCC) and HbA(1c) Integra (IFCC) against HbA(1c) D-10 (NGSP) were -1.90% and -1.79%, respectively. Kappa agreement statistics for the three diabetic control group HbA(1c) values of “less than 6.5%,” “6.5%-7.5%,” and “greater than 7.5%” for D-10 vs. Turbo, D-10 vs. Integra, and D-10 vs. Afinion were 0.872, 0.836, and 0.833, respectively.\n\nConclusions : The strong correlations and good clinical agreements of HbA(1c) between each analyzer expressed in terms of either NGSP or IFCC-derived NGSP indicate that these analyzers can

be used interchangeably. (Korean J Lab Med 2010:30:345-50)”
“Background: Vitamin K is an essential element in the coagulation, which is also involved in gamma-carboxylation reactions of proteins as osteocalcin, which may exert a protective effect against age-dependent Ferroptosis inhibitor bone loss. But there is also evidence that both osteocalcin as vitamin K can have a benefit on the metabolism of glucose, insulin sensitivity and type 2 diabetes mellitus. Therefore, the aim of the present study is to analyse the adequacy of vitamin K intake and food sources in a representative sample of Spanish adults. Methods: A sample of 1068 adults (521 men and 547 women) with ages ranging from 17 to 60 years, was selected in ten Spanish provinces to constitute a representative sample of the population nationwide. The dietary study was carried

out by using a “Food record questionnaire” for 3 consecutive days, including a Sunday. Personal, anthropometric and health data were also collected. Results: The intake of vitamin K (170.2 +/- 14.5 mu g/day) was lower than the established adequate intake for vitamin in the 30.2% of the studied selleck participants. Vitamin

intake increases with age (r = 0.201, p smaller than 0.05), in fact, those participants who meet the adequate intake are older (34.5 +/- 12.8 years) than those who do not meet the adequate intake (with a mean age 29.1 +/- 11.9 years) (p smaller than 0.001). Vitamin K intake also increases with weight (r = 0.106, p smaller than 0.05) and height (r = 0.282, p smaller than 0.05), however the participants with overweight/obesity have a significantly lower intake (168.2 +/- 13.5 g/day) than those individuals with normal weight (171.1 +/- 14.9 mu g/day) (p smaller than 0.01). The major food source of vitamin K are vegetables (45.35% of the intake comes from this food group), followed by fats and oils (13.28%), pulses (11.69%), meat (10.62%), cereals (5.33%) and fruits (4.60%). Meeting adequate intake for vitamin K is favoured by the increase in the consumption of vegetables (OR 0.329; CI95%: 0.279, 0.387), dairy (OR 0.815; CI95%: 0.690, 0.963), pulses (OR 0.091; CI95 % : 0.054, 0.154) and fruits (OR 0.774; CI95 %: 0.677, 0.885) (p smaller than 0.001). A positive correlation was found between vegetable consumption and the intake of vitamin K (r = 0.432, p smaller than 0.001).

In conclusion, low, Selleckchem HDAC inhibitor but not high, frequency stimulation activated a withdrawal response which appears mediated by morphine and capsaicin sensitive primary afferents and this threshold was reduced in the presence of inflammation. These data suggest the validity of such stimulation

in defining drug action in a nontissue injurious fashion. (c) 2007 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.”
“Despite the widespread use of intensity-modulated radiation therapy (IMRT) for approximately a decade, a lack of adequate guidelines for documenting these treatments persists. Proper IMRT treatment documentation is necessary for accurate reconstruction of prior treatments when a patient presents with a marginal recurrence. This is especially crucial when the follow-up Nepicastat molecular weight care is managed at a second treatment facility not involved in the initial IMRT treatment. To address this issue, an American Society for Radiation Oncology (ASTRO) workgroup within the American ASTRO Radiation Physics Committee was formed at the request of the ASTRO Research Council to develop a set of recommendations for documenting IMRT treatments. This document provides a set of comprehensive recommendations for documenting

IMRT treatments, as well as image-guidance procedures, with example forms provided. (C) 2009 Elsevier Inc. All rights reserved.”
“In the two anions of the title salt, C(2)H(10)N(2)(2+)center dot 2C(8)H(5)N(8)(-)center dot 2H(2)O, the central aromatic rings make dihedral angles of 13.53 (6)

and 6.53 (7)degrees with the deprotonated tetrazole rings, and 11.39 (6) and 10.41 (9)degrees with the other tetrazole groups. In the crystal, the cations, anions and water molecules are linked by an extensive O-H center dot center dot center dot N, N-H center dot center dot center dot O and N-H center dot center dot center dot N hydrogen-bond see more network into two-dimensional wave-like duplex sheets extending parallel to the bc plane. pi-pi stacking interactions between benzene rings [intercentroid distances are 3.8482 (4) and 3.9621 (5) angstrom] and between tetrazole rings [intercentroid distances are 3.4350 (4) and 3.7169 (4) angstrom] further consolidate the crystal structure.”
“P>Background.\n\nRecurrent aphthous stomatitis (RAS) presents a diagnostic problem in Behcet’s disease (BD), particularly when it occurs as the only or earliest feature of the disease. To date, there have been only a few reports studying the differences in characteristics between RAS and BD.\n\nAim.\n\nTo examine the clinical differences between RAS and BD using a large group of patients.\n\nMethods.\n\nA retrospective review was carried out, analysing demographic data, the clinical features of the oral ulcer, and the major and minor symptoms of BD of 1643 patients with RAS and 3527 patients with BD presenting from 1995 to 2001.\n\nResults.

Some VitC deficient Gulo(-/-) mice received an infusion of ascorbic acid (AscA, 200 mg/kg) 30 min after induction of FIP. NETosis was assessed histologically and by quantification for circulating free DNA (cf-DNA) in serum. Autophagy, histone citrullination, endoplasmic reticulum (ER) stress, NF kappa B activation and apoptosis were investigated in peritoneal PMNs. Results: Sepsis produced significant NETs in the lungs of VitC deficient Gulo(-/-) mice and increased

SCH727965 circulating cf-DNA. This was attenuated in the VitC sufficient Gulo(-/-) mice and in VitC deficient Gulo(-/-) mice infused with AscA. Polymorphonuclear neutrophils (PMNs) from VitC deficient Gulo(-/-) mice demonstrated increased activation of ER stress, autophagy, histone citrullination, and NF kappa B activation, while apoptosis was inhibited. VitC also significantly attenuated PMA induced NETosis in PMNs from healthy human volunteers. Conclusions: Our in vitro and in vivo

findings identify VitC as a novel regulator of NET formation in sepsis. This study complements the notion that VitC is protective in sepsis settings.”
“To study the internal structure and the convergent and divergent validity of the Multicultural Quality of Life Index (MQLI) in a Spanish sample.\n\nThe MQLI, along with another quality of life instrument-the World Health Organization Quality of Life, brief version (WHOQOL-BREF)-and the Depression, CA3 cost Anxiety and Stress Scales (DASS-21), was administered to 356 students, 159 people from the general population and 65 psychiatric patients.\n\nThe value of Cronbach’s alpha was .90. The confirmatory factor analysis showed a good fit for both the one- and two-factor structures. The overall mean score of the MQLI https://www.selleckchem.com/products/LDE225(NVP-LDE225).html correlated between .61 and .78 with the domains of the WHOQOL-BREF and between -.55 and -.70 with the DASS-21 scales.\n\nThe MQLI has high internal consistency, can be interpreted in terms of a single factor, and has an adequate convergent validity, although its

absolute correlations with depression and with the WHOQOL-BREF were equally high.”
“A DNA-guided method for surface engineering of NaGdF4:Ce/Tb hybrid nanoparticle has been proposed. In this study, the DNA molecules that retained after one-pot NaGdF4:Ce/Tb synthesis is directly utilized as biotemplate for CaP heterogeneous nucleation, thus the dual-purpose function of DNA is realized in the current study which could afford a new type of pH-responsive theranostic platform to enhance the therapeutic efficiency while minimizing side effects. The introduction of another layer of aptamer molecules on CaP facilitated cellular uptake of the resulting nanocomposite into specific target cells via receptor-mediated endocytosis.

Oral health-related quality of life was assessed NCT-501 using the Brazilian version of the Child Perceptions Questionnaire (CPQ(11-14)) – Impact Short Form (ISF:16), composed of 16 items and self-administered by all children. Other oral conditions (dental caries and malocclusion) and the Social Vulnerability Index were determined and used as controlling variables.\n\nResults: Two hundred nineteen children were diagnosed with untreated TDI and 64 were diagnosed with treated

TDI. There were no statistically significant associations between untreated or treated TDI and overall CPQ(11-14) (Fisher = 0.368 and Fisher = 0.610, respectively). Children with an untreated TDI were 1.4-fold (95% CI = 1.1-2.1) more likely to report impact on the item “avoided smiling/laughing” than those without TDI, whereas children with a treated TDI were twofold (95% CI = 1.1-3.5) more likely to report impact on the item “other children asked questions” than those without TDI.\n\nConclusions: Neither BI 6727 purchase treated nor untreated TDI was associated with

oral symptoms, functional limitations or emotional wellbeing. However, children with a TDI in the anterior teeth experienced a negative impact on social wellbeing, mainly with regard to avoiding smiling or laughing and being concerned about what other people may think or say.”
“Exploiting the plasmon resonance of gold nanoparticles and the ability to specifically target cancer cell surface proteins, photoacoustic flowmetry may be used to detect nonpigmented circulating tumor cells (CTCs). AG-881 cell line The authors targeted the EpCAM receptors to attach 50-nm gold nanoparticles to a breast cancer cell line, T47D. After determining the absorption peak and thus the most sensitive laser wavelength, they performed serial dilution trials to show detection of small numbers of breast

cancer cells in suspension. This ability may allow an earlier clinical diagnosis and management of metastatic disease for a range of solid tumor types.”
“Background: Different patterns of drug resistance are observed in treated and therapy naive HIV-1 infected populations. Especially the NRTI-related M184I/V variants, which are among the most frequently encountered mutations in treated patients, are underrepresented in the antiretroviral naive population. M184I/V mutations are known to have a profound effect on viral replication and tend to revert over time in the new host. However it is debated whether a diminished transmission efficacy of HIV variants with a reduced replication capacity can also contribute to the observed discrepancy in genotypic patterns. As dendritic cells (DCs) play a pivotal role in HIV-1 transmission, we used a model containing primary human Langerhans cells (LCs) and DCs to compare the transmission efficacy M184 variants (HIV-M184V/I/T) to HIV wild type (HIV-WT).

The primary end point was progression-free survival (PFS). Results Median PFS from time of random assignment was 3.7 months with bevacizumab/placebo and 4.8 months with bevacizumab/erlotinib (hazard ratio [HR], 0.71; 95% CI, 0.58 to 0.86; P smaller than .001). Median overall survival (OS) times from random assignment were 13.3 and 14.4 months with bevacizumab/placebo and bevacizumab/erlotinib, respectively (HR, 0.92; 95% CI, 0.70 to 1.21; P = .5341). During the postchemotherapy phase, there were more adverse events (AEs) overall,

more grade 3 and 4 AEs (mainly rash and diarrhea), more serious AEs, and more AEs leading to erlotinib/placebo Batimastat cell line discontinuation in the bevacizumab/erlotinib arm versus the bevacizumab/placebo arm. The incidence of AEs leading to bevacizumab discontinuation

was similar in both treatment arms. Conclusion The addition of erlotinib to bevacizumab significantly improved PFS but not OS. Although generally well tolerated, the modest impact on survival and increased toxicity associated with the addition of erlotinib to bevacizumab maintenance mean that this two-drug maintenance regimen will not lead to a new postchemotherapy standard of care. (C) 2013 by American Society of Clinical Oncology”
“The Afrotropical representatives of the spider high throughput screening assay genus Cheiracanthium C. L. Koch, 1839 from Madagascar and the Comoros Islands are revised, and new species are described. Five described species are recognized: C. africanum Lessert, 1921, C. furculatum Karsch, 1879, C. insulare (Vinson,

find more 1863), C. leucophaeum Simon, 1896, and C. ludovici Lessert, 1921. The internal genitalia of the female of C. insulare, and the female of C. ludovici, are described for the first time. Thirteen new species, C. ambrense sp. nov. (male female), C. ampijoroa sp. nov. (female), C. andranomay sp. nov. (female), C. anjozorobe sp. nov. (male female), C. ashleyi sp. nov. (male female), C. fisheri sp. nov. (male female), C. foulpointense sp. nov. (male female), C. griswoldi sp. nov. (male female), C. jocquei sp. nov. (male female), C. madagascarense sp. nov. (male female), C. mahajanga sp. nov. (female), C. ransoni sp. nov. (male female) and C. rothi sp. nov. (male female), are described. In most of the endemic Madagascan species the female genital depression is divided by a central septum and the male cymbial apophysis is bent distally.”
“Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis and visceral involvement, and localized scleroderma or morphea which classically presents benign and self-limited evolution and is confined to the skin and/or underlying tissues. Localized scleroderma is a rare disease of unknown etiology.

“
“In non-neuronal cells, inactivation of protein kinase D (PKD) blocks fission of trans-Golgi network (TGN) transport carriers, inducing the appearance of long tubules filled with cargo.

We now report on the function of PKD1 in neuronal protein trafficking. In cultured hippocampal pyramidal cells, the transferrin receptor (TfR) and the low-density receptor-related protein (LRP) are predominantly transported to dendrites and excluded from axons. Expression of kinase-inactive PKD1 or its depletion by RNA interference treatment dramatically and selectively alter the intracellular trafficking and membrane delivery of TfR- and LRP-containing vesicles, without inhibiting exit from the TGN Anlotinib or inducing Golgi

tubulation. After PKD1 suppression, dendritic membrane proteins are mispackaged into carriers that transport VAMP2; these vesicles are distributed to both axons and dendrites, but are rapidly endocytosed from dendrites and preferentially delivered to the axonal membrane. A kinase-defective mutant of PKD1 lacking the ability to bind diacylglycerol and hence its Golgi localization does not cause missorting of TfR or LRP. These results suggest that in neurons PKD1 regulates TGN-derived sorting of dendritic proteins and hence has a role in neuronal polarity.”
“Riluzole is the only drug approved for the treatment of amyotrophic lateral sclerosis (ALS) but its precise mode of action is not properly understood. Damage to axonal transport of neurofilaments is believed to be part of GSK2245840 the pathogenic mechanism in ALS and this has been selleck chemical linked to defective glutamate handling and increased phosphorylation of neurofilament side-arm domains. Here, we show that riluzole protects against glutamate-induced slowing of neurofilament transport. Protection is associated with decreased neurofilament side-arm phosphorylation and inhibition of the activities

of two neurofilament kinases, ERK and p38 that are activated in ALS. Thus, the anti-glutamatergic properties of riluzole include protection against glutamate-induced changes to neurofilament phosphorylation and transport. (C) 2009 Elsevier Ireland Ltd. All rights reserved.”
“We herein report the synthesis and characterization of ABA triblock copolymers that contain two complementary association motifs and fold into single-chain polymeric nanoparticles (SCPNs) via orthogonal self-assembly. The copolymers were prepared using atom-transfer radical polymerization (ATRP) and possess different pendant functional groups in the A and B blocks (alcohols in the A block and acetylenes in the B block). After postfunctionalization, the A block contains o-nitrobenzyl-protected 2-ureidopyrimidinone (UPy) moieties and the B block benzene-1,3,5-tricarboxamide (BTA) moieties.

The efficiency of luciferase gene transfection of lipoplexes 1-3 was compared with that of commercial dioleoyl-trimethylammonium propane (DOTAP) and polyethyleneimine (PEI) in 293T cells and BMS-777607 research buy HepG2 cells with or without poly(ethylene glycol) PEG stabilizer. The

complexation and protection of DNA of liposome 3 was the strongest among the three liposomes. The efficiency of gene transfection of liposomes 1-3 was two-to threefold higher than that of PEI and/or DOTAP in 293T cells. Liposomes 1 and 3 in PEG as stabilizer showed sixfold higher transfection efficiency than that of PEI and/or DOTAP, whereas liposome 2 showed very low transfection efficiency. In HepG2 cells, the transfection efficiency of all the cationic liposomes was much lower than that of DOTAP. In conclusion, lipids 1-3 were efficient and non-toxic gene vectors; the headgroup of cationic lipids and the stabilizer of liposome formulation had an important influence on gene transfection.”
“The abortive properties and the clinical and pathological features Selleckchem AZD1208 of poisoning by the pods of Stryphnodendron fissuratum were studied in 8 pregnant goats. Two goats that ingested 3.25 g/kg body weight daily doses for 2 days, and 2 that ingested 2.5 g/kg daily doses for 3 days showed digestive clinical signs and aborted, but the animals that ingested 3 daily doses of 2.5 g/kg died. Lesions of the digestive system

and liver were observed at necropsy. Two goats that ingested a single dose of 5.5 g/kg showed mild clinical signs and recovered without abortion. Another 2 goats that ingested single doses of 5 g/kg showed no clinical signs. These results demonstrate that Stryphnodendron fisuratum pods cause digestive disorders, liver disease, abortion selleck and death. (C) 2011 Elsevier Ltd. All rights reserved.”
“Hypocalcaemia is a rare complication of calcium channel blocker overdose, having been reported only once previously (J Toxicol Clin Toxicol, 1992, 30, 309). In this article,

we report a case of a 37-year-old woman who developed hypocalcaemia after a verapamil overdose, review the literature and propose a mechanism for this rare finding.”
“BACKGROUND: Breast-associated morphea (BAM) can mimic benign and malignant inflammatory breast disorders. The aim of the current study was to document our experience with this rare sclerosing dermatologic disorder.\n\nMETHOD: We conducted a retrospective study at a single institution of all patients who had pathological diagnosis of morphea between January 1995 and October 2007.\n\nRESULTS: We identified 15 patients with pathological evidence of morphea involving the breast. Two thirds of these patients were initially misdiagnosed with inflammatory breast cancer or breast infections. While 2 patients had previous exposure to external beam radiation, the remaining patients had no identifiable predisposing risk factors.

Here, we characterize the biology of two SGSs in the malaria mosquito, Anopheles gambiae, and demonstrate their involvement in blood feeding. Western blots and RT-PCR showed that Sgs4 and Sgs5 are produced exclusively

in female salivary glands, that expression increases with age and after blood feeding, and that protein levels fluctuate in a circadian manner. 5-Fluoracil purchase Immunohistochemistry showed that SGSs are present in the acinar cells of the distal lateral lobes and in the salivary ducts of the proximal lobes. PAGE, Western blots, bite blots, and immunization via mosquito bites showed that SGSs are highly immunogenic and form major components of mosquito saliva. Last, Western and bioinformatic analyses suggest that SGSs are secreted via a non-classical pathway that involves cleavage into a 300-kDa soluble fragment and a smaller membrane-bound fragment. Combined, these data strongly suggest that SGSs play an important role in blood feeding.

Together with their role in malaria transmission, we propose that SGSs AZD9291 order could be used as markers of human exposure to mosquito bites and in the development of disease control strategies.”
“Endochondral ossification is a highly regulated process that relies on properly orchestrated cell-cell interactions in the developing growth plate. This study is focused on understanding the role of a crucial regulator of cell-cell interactions, the membrane-anchored metalloproteinase ADAM17, in endochondral ossification. ADAM17 releases growth factors, cytokines, P505-15 molecular weight and other membrane proteins from cells and is essential for epidermal growth factor receptor (EGFR) signaling and for processing tumor necrosis factor alpha. Here, we report that mice lacking ADAM17 in chondrocytes (A17 Delta Ch) have a significantly expanded zone of hypertrophic chondrocytes in the growth plate and

retarded growth of long bones. This abnormality is caused by an accumulation of the most terminally differentiated type of chondrocytes that produces a calcified matrix. Inactivation of ADAM17 in osteoclasts or endothelial cells does not affect the zone of hypertrophic chondrocytes, suggesting that the main role of ADAM17 in the growth plate is in chondrocytes. This notion is further supported by in vitro experiments showing enhanced hypertrophic differentiation of primary chondrocytes lacking Adam17. The enlarged zone of hypertrophic chondrocytes in A17 Delta Ch mice resembles that described in mice with mutant EGFR signaling or lack of its ligand transforming growth factor alpha (TGF alpha), suggesting that ADAM17 regulates terminal differentiation of chondrocytes during endochondral ossification by activating the TGF alpha/EGFR signaling axis.”
“Background: To our knowledge, no prospective study has examined the association between vitamin D and cognitive decline or dementia.

The current data also do not support recent recommendations to delay administration until pH is normalized.”
“So far the determination of unitary permeability (p(f)) of water channels that are expressed in polarized cells is subject to large errors because the opening of a single water channel does not noticeably increase the water permeability of a membrane patch above the background. That is, in contrast to the patch clamp technique,

where the single ion channel conductance may be derived from a single experiment, two experiments separated in time and/or space are required to obtain the single-channel water permeability p(f) as a function of the incremental water permeability (p(f, c)) and the number (n) of water channels that contributed to p(f, c). Although the unitary conductance of ion channels is measured in the native environment of the channel, p(f) is so far

derived from reconstituted channels or channels expressed ARN-509 purchase in oocytes. To determine the p(f) of channels from live epithelial monolayers, we exploit the fact that osmotic volume flow alters the concentration of aqueous reporter dyes adjacent to the epithelia. We measure these changes by fluorescence correlation spectroscopy, which allows the calculation of both p(f, c) and osmolyte dilution within the unstirred layer. Shifting the focus of the laser from the aqueous solution to the apical and basolateral membranes allowed the FCS-based determination of n. Here we validate the HM781-36B new technique by determining

the p(f) of aquaporin 5 in Madin-Darby canine kidney cell monolayers. Because inhibition and subsequent activity rescue are monitored on the same sample, drug effects on exocytosis or endocytosis can be dissected from those on p(f).”
“The housefly Musca domestica L. is recognized as a public health pest causing a serious threat to human and livestock by vectoring many infectious diseases. Chemical control method commonly used against this pest, though effective, has some major disadvantages, such as development of insect resistance and bioaccumulation. Pest management strategies for populations of houseflies are needed. Presently, bioinsecticides, Selumetinib concentration especially those derived from plant origin, have been increasingly evaluated in controlling insects of medical importance. In order to search for effective and ecofriendly control agents, the essential oils of Mentha piperita, Zingiber officinalis, Emblica officinalis, and Cinnamomum verum were evaluated for their larvicidal, attractant/repellent, and oviposition attractant/deterrent activity against M. domestica. The highest larvicidal activity, i.e., C-50 = 104 ppm was shown by M. piperita. This oil also exhibited 96.8 % repellency at the concentration of 1 %. The highest oviposition deterrence activity of 98.1 % was also exhibited by M. piperita oil at the concentration of 1 %. Among the remaining plants, the essential oil of Z.

Theory and corresponding frameworks indicate a wide range of factors affecting access to health care, such as traditionally measured variables (distance to a health provider and cost of obtaining health care) and additional variables (social support, time availability and caregiver autonomy). Few analytical studies of traditional variables have been conducted in SSA, and they GDC-0068 nmr have significant limitations and inconclusive results. The importance of additional factors has been suggested

by qualitative and recent quantitative studies. We propose that access to health care is multidimensional; factors other than distance and cost need to be considered by those planning health care provision if child mortality rates are to be reduced through improved access. Analytical studies that comprehensively evaluate both traditional and additional variables

in developing countries are required.”
“Objectives: To describe the proportion of women reporting time is a barrier to healthy eating and physical activity, the Selleckchem Y 27632 characteristics of these women and the perceived causes of time pressure, and to examine associations between perceptions of time as a barrier and consumption of fruit, vegetables and fast food, and physical activity.\n\nDesign: A cross-sectional survey of food intake, physical activity and perceived causes of time pressure.\n\nSetting: A randomly selected community sample.\n\nSubjects: A sample of 1580 women self-reported their food intake and their perceptions of the causes of time pressure in relation to

healthy eating. An additional 1521 women self-reported their leisure-tune physical activity and their perceptions of the causes of time pressure in relation to physical activity.\n\nResults: Time pressure was reported as a barrier to healthy eating by 41% of Transmembrane Transporters inhibitor the women and as a barrier to physical activity by 73%. Those who reported time pressure as a barrier to healthy eating were significantly less likely to meet fruit, vegetable and physical activity recommendations, and more likely to eat fast food more frequently.\n\nConclusions: Women reporting time pressure as a barrier to healthy eating and physical activity are less likely to meet recommendations than are women who do not see time pressure as a barrier. Further research is required to understand the perception of time pressure issues among women and devise strategies to improve women’s food and physical activity behaviours.”
“We present a general formalism where different levels of coupled cluster theory can be applied to different parts of the molecular system. The system is partitioned into subsystems by Cholesky decomposition of the one-electron Hartree-Fock density matrix. In this way the system can be divided across chemical bonds without discontinuities arising.