The dose of crocin was selected based on the amount present in 50 mg of saffron. The effect on cellular immunity was evaluated using the neutrophil adhesion test, cyclophosphamide-induced neutropenia and carbon clearance assay, while the effect on humoral immunity was studied using the mice lethality test, serum immunoglobulins estimation and

the indirect haemagglutination assay. The results revealed that Crocus sativus and crocin stimulate both cellular and humoral immune responses. Both these agents https://www.selleckchem.com/products/ldk378.html produced a significant increase in adhesion of neutrophils, attenuation of cyclphosphamide-induced neutropenia and an increase in phagocytic index in carbon clearance assay indicating their effect on cellular immunity. The effect on humoral immune response was demonstrated by reduction in mortality in the mice lethality assay, a rise in serum immunoglobulin levels and an increase in thymus gland weight and haemagglutination titre value.”
“Borderline ovarian tumor with the initial presentation of pseudo-Meigs’ syndrome is rare. A 52-year-old postmenopausal woman presented with a large ovarian tumor, ascites, and right hydrothorax. We found elevated serum carcinoembryonic antigens (44.4 ng/mL), carbohydrate antigen (CA)-125 (269.8 U/mL), and CA-199 (7942 U/mL). The frozen section pathology revealed a mucinous

borderline ovarian tumor, and a staging operation was performed. Final pathologic examination confirmed the diagnosis of intestinal type ovarian mucinous borderline tumor with non-invasive cul-de-sac implants. Her pleural effusion and ascites resolved after surgery, and she remained tumor-free after LDC000067 in vivo 3 years’ follow up. Physicians should be cautious for the rare possibility of pseudo-Meigs’ syndrome in patients with pelvic tumors having the features of advanced ovarian cancer.”
“The aim of this work was to develop clozapine tablets that can be classified as a pharmaceutical equivalent to a reference brand product. Tablets were produced by direct compression and dissolution tests were realized in order to evaluate the

dissolution profiles. The results show that the tablets can be classified as immediate release dosage forms due to clozapine fast release, and such release was dependent on the amount of sodium croscarmelose in the formulation. Analysis Selleck Dinaciclib of f1 and f2 factors was frustrated due to the fast drug release; the tablets were analyzed by the dissolution efficiency and the dissolution curve shape. The dissolution efficiency was higher than 98 % and the analysis of the dissolution shape curve showed that the tablets from one batch of the developed formulations were similar to the reference brand product. The clozapine tablets obtained in this study can be considered as pharmaceutically equivalent to the reference brand product.”
“Paraovarian tumor of borderline malignancy is rare. Only 13 cases in Japan, including the present cases, and 40 cases overseas have been reported.