Methods The preparation of S/GNS composite is represented in Figure 1a. Sulfur (high purity, GOST 127.1, Tengizchevroil, Atyrau, Kazakhstan) and graphene nanosheets (US Research Nanomaterials Inc., Houston, TX, USA) were mixed in the weight ratio of 3:1 and wet ball-milled (Pulverisette 7 Selleck Enzalutamide classic line, Fritsch, Idar-Oberstein, Germany) at 800 rpm for 3 h with ethanol as a dispersant. The precursor mixture was further dried in a vacuum oven at 60°C for 3 h, dry ball-milled at 600 rpm for 6 h, and then heat-treated at 150°C for 6 h in a tube furnace in argon. The sulfur

content in the final S/GNS composite was 65 wt% as determined by chemical AMG510 analysis (CHNS, vario MICRO cube, Elementar, Hanau, Germany). Figure 1 Schematics of the preparation process. Schematic diagrams of the synthesis of (a) S/GNS composite and (b) PVDF-HFP/PMMA/SiO2 polymer matrix. The preparation of the GPE is schematically represented in Figure 1b. Among other polymer pore-making technologies, we adopted the phase inversion method to obtain a porous structured system through a solvent exchange route [23, 24]. The membrane is formed by polymer precipitation, which occurs as a consequence of concentration variations following diffusive interchange between the solvent (acetone) and the non-solvent (water). PVDF-HFP (KynarFlex 2801, Arkema Inc., Philadelphia, PA, USA), PMMA (average molecular weight 350,000 g mol−1, Protein Tyrosine Kinase inhibitor Sigma-Aldrich,

St. Louis, MO, USA), and SiO2 nanopowder (US Research Nanomaterials, Inc.) were added to acetone in a weight ratio of 3:2:0.25 under stirring followed by sonication. Deionized water was then added dropwise and the mixture was continuously stirred for 3 h. The resulting slurry was cast on an aluminum plate and the solvent was evaporated overnight at ambient temperature. The resulting membrane was dried under vacuum at 50°C for 5 h. The resulting mechanically stable membranes, approximately 80 μm thick, were activated inside an argon-filled glove box (As One Co., Osaka, Japan) by immersion in a 1 mol dm−3 solution of lithium bistrifluoromethanesulfonamide

(LiTFSI) Interleukin-2 receptor in tetraethylene glycol dimethyl ether (99.95% purity, Sigma-Aldrich). The liquid uptake (%) was determined using the relation (W 2 − W 1) × 100/W 1, where W 1 and W 2 denote the respective weights of the polymer electrolyte before and after absorbing the lithium salt solution [25]. The S/GNS composite surface morphology was examined by field emission scanning electron microscopy (SEM; JSM-6490, JEOL, Akishima, Tokyo, Japan). The interior structure of the composite was observed by transmission electron microscopy (TEM; High Voltage LIBRA 120, Сarl Zeiss, Oberkochen, Germany) with energy-dispersive X-ray spectroscopy (EDX). The ionic conductivity of the GPE was determined at 25°C by electrochemical impedance spectroscopy (EIS) over the frequency range from 0.