Infect Immun 2001, 69 (7) : 4366–4372.PubMedCrossRef 5. Chow JW, Thal LA, Perri MB, Vazquez

JA, Donabedian SM, Clewell DB, Zervos MJ: Plasmid-associated hemolysin and aggregation substance production contribute to virulence in experimental enterococcal endocarditis. Antimicrob Agents Chemother 1993, 37 (11) : 2474–2477.PubMed 6. Jett BD, Jensen HG, Nordquist RE, Gilmore MS: Contribution of the pAD1-encoded cytolysin to the severity of experimental Enterococcus faecalis endophthalmitis. Infect Immun 1992, 60 (6) : 2445–2452.PubMed selleck compound 7. Schlievert PM, Gahr PJ, Assimacopoulos AP, Dinges MM, Stoehr JA, Harmala JW, Hirt H, Dunny GM: Aggregation and binding substances enhance pathogenicity in rabbit models of Enterococcus faecalis endocarditis. Infect Immun 1998, 66 (1) : 218–223.PubMed 8. Singh KV, PD-1/PD-L1 Inhibitor 3 datasheet Nallapareddy SR, Sillanpaa J, Murray BE: Importance of the collagen adhesin ace in pathogenesis and protection against Enterococcus faecalis experimental endocarditis. PLoS Pathog 6 (1) : e1000716. 9. Kreft B, Marre R, Schramm U, Wirth R: Aggregation substance of Enterococcus faecalis mediates adhesion to cultured renal tubular cells. Infect Immun 1992, 60 (1) : 25–30.PubMed 10. Olmsted SB, Dunny GM, Erlandsen SL, Wells CL: A plasmid-encoded surface protein on Enterococcus

faecalis augments its internalization by cultured intestinal epithelial cells. J Infect Dis 1994, 170 (6) : 1549–1556.PubMedCrossRef 11. Shankar V, Baghdayan AS, Huycke MM, Lindahl G, Gilmore MS: Infection-derived Enterococcus faecalis strains are enriched check details in esp , a gene encoding a novel surface protein. Infect Immun 1999, 67 (1) : 193–200.PubMed 12. Rice LB, Carias L, Rudin S, Vael C, Goossens H, Konstabel C, Klare I, Nallapareddy SR, Huang W, Murray BE:

A potential virulence gene, hyl Efm , predominates in Enterococcus faecium of clinical origin. J Infect Dis 2003, 187 (3) : 508–512.PubMedCrossRef 13. Nallapareddy SR, Sillanpaa J, Ganesh VK, Hook M, Murray BE: Inhibition of Enterococcus faecium adherence to collagen by antibodies against high-affinity binding subdomains of Acm. Infect Immun 2007, 75 (6) : 3192–3196.PubMedCrossRef buy Decitabine 14. Sillanpaa J, Nallapareddy SR, Prakash VP, Qin X, Hook M, Weinstock GM, Murray BE: Identification and phenotypic characterization of a second collagen adhesin, Scm, and genome-based identification and analysis of 13 other predicted MSCRAMMs, including four distinct pilus loci, in Enterococcus faecium . Microbiology 2008, 154 (Pt 10) : 3199–3211.PubMedCrossRef 15. Hendrickx AP, van Luit-Asbroek M, Schapendonk CM, van Wamel WJ, Braat JC, Wijnands LM, Bonten MJ, Willems RJ: SgrA, a nidogen-binding LPXTG surface adhesin implicated in biofilm formation, and EcbA, a collagen binding MSCRAMM, are two novel adhesins of hospital-acquired Enterococcus faecium . Infect Immun 2009, 77 (11) : 5097–5106.PubMedCrossRef 16.