He was discharged from the hospital on the 86th POD, after physical rehabilitation. He has resumed daily life and is free from complications more than 33 months after surgery. Review of reported

cases There are only two reports of a gastropericardial fistula of a gastric tube ulcer after esophagectomy [1, 5]. The other 26 cases of pericardium-penetrating U0126 clinical trial gastric tube ulcers have been Tariquidar order reported in Japan, mostly Japanese conference proceedings or case reports in Japanese. All 29 cases, including the current case, are listed in Table 2; all cases were reconstructed via a retrosternal route, except two via a posterior mediastinum, one via intra-thorax, and one unknown case. Postoperative durations vary from 2 months up to 12 years. Initial symptoms are usually chest pain or chest discomfort, with 12 patients (41%) initially presenting at cardiovascular/internal medicine or general practitioners. The current case was presented to and primarily treated by cardiologists. Conservative therapy, percutaneous pericardial drainage, or surgical drainage was adopted for 10 (37%), eight (30%), and nine patients (33%), respectively (Table 2). Thirteen patients were rescued, three in 10 by conservative therapies, two in six with trans-cutaneous drainage, including one that eventually needed additional surgical treatment, and eight in nine in surgical drainage; rescue ratios of 30%, 33%, and 89%, respectively.

Prognosis in surgical drainage is much better than that in conservative AZD8931 mw therapies or in percutaneous drainage. Table 2 Reported cases of gastropericardial fistula PTK6 of gastric tube ulcer since 1984, quoted and partially modified from a report by Shibutani et al.   Patient Time between   Case Report year Age Sex surgery and onset Reconstruction route Primary symptom Initial treatment Modality for therapy Outcome Reference 1 1984 46 Male 2 years 5 months Retrosternal Shock Surgery Conservative Death C. P.* [14] 2 1989 58 Male 3 years Retrosternal Chest pain, tachycardia Internal medicine Not described Death C. P.* [15] 3 1991 67 Male 3 months Retrosternal Precordial pain Surgery Conservative

Death ref. [1] 4 1993 66 Male 9 years Retrosternal Chest pain Internal medicine Conservative Death C. P.* [16] 5 1993 57 Female 4 years Intra-thoracic Retrosternal pain Internal medicine Not described Death C. P.* [17] 6 1996 66 Male 1 year 9 months Posterior mediastinal Chest pain Surgery Conservative Rescued [18] 7 1997 74 Male 8 years Retrosternal Precordial pain Surgery Surgical drainage (left thoracotomy) Rescued [19] 8 1998 62 Male 2 months Retrosternal Shock Surgery Conservative Death [20] 9 1998 N/A   2 years Retrosternal Shock Surgery Surgical drainage (left thoracotomy → right thoracotomy) Death C. P.* [21] 10 1999 56 Male 2 years 5 months Retrosternal Precordial pain Internal medicine Surgical drainage, partial resection of gastric tube Rescued C. P.