Adequate specimen for histological assessment was obtained in 87 patients (93.5%). The sensitivity, specificity, and accuracy in the diagnosis of SMT by EUS-FNA were 91%, 100%, and 94%, respectively. Finally, 51 patients underwent surgery and surgical diagnoses were GIST in 44, leiomyoma in 5, Selleckchem LDK378 schwannoma in 1, and metastatic cancer in 1. Of the 42 patients with surgical diagnosis of GIST, weighted kappa coefficients between FNA and surgical specimens in
modified Fletcher risk classification was 0.92. No procedure-related complication was observed. Conclusion: EUS-FNA using a 19-gauge needle was a safe and reliable procedure to obtain the histopathological diagnosis. It is also useful to assess the risk classification of GIST preoperatively.
Key Word(s): 1. EUS-FNA; 2. GIST Presenting Author: IK MARIADI Additional Authors: IW DARYA, IDN WIBAWA, N PURWADI, IGA SURYADARMA Corresponding Author: IK MARIADI Affiliations: Department of Internal Medicine, Sanglah General Hospital/ Udayana University School of Medicine Denpasar, Indonesia Introduction: Screening populations using endoscopy is impractical and selleck chemicals llc expensive. We need a noninvasive method to choose the patient that really need endoscopy. We evaluate the accuracyof gastrin-17 as a tool of screening patientsfor endoscopy. Method: Endoscopy finding wasclassified in 2 category, severe and mild/normal, severe if we found ulcer or tumor in gastric and mild if we found normal, superficial and erosive gastritis. Fasting serum gastrin-17 was determined by standard immunoassays. Receiving operating characteristic (ROC) analysis was used to determine the 上海皓元医药股份有限公司 best cut-off for gastrin-17 serum test in severe and mild/normal endoscopic feature.
Results: Seventy seven patients underwent endoscopy. Seventy one patients with normal/mild finding and 6 patients with severe finding. Base on nonparametric test with MannWhitney test, we found significant mean different of gastrin-17 between mild/normal and severe group (p = 0.025). Diagnostic accuracy of Gastrin-17 on determining severe finding base on ROC procedure, we found AUC 78% (95% CI: 63%-91%), p = 0.025, with sensitivity and sensitivity are 66.7% and 77.5% at value ≥ 21.75 pg/ml. Conclusion: In dyspepsia patient, Gastrin-17 has anacceptable accuracy in determining severe abnormality on endoscopy and value ≥ 21.75 pg/ml is the best cut off value for screening severe endoscopic feature. Keyword(s): 1. Gastrin-17; 2. endoscopy feature Presenting Author: LUBIS MASRUL Additional Authors: ALAMSYAH SIREGAR GONTAR, HAKIM ZAIN LUKMAN Corresponding Author: LUBIS MASRUL Affiliations: Gastroenterology-Hepatology Division Internal Medicine Department – Haji Adam Malik General Hospital Objective: Endoscopy has been used with increasing frequency in the investigation of upper gastrointestinal symptoms.